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Gynaecology guide

Perimenopause and Menopause

Understanding cycle changes, hot flushes, sleep symptoms, vaginal health and evidence-based treatment options.

This guide supports an informed consultation and is not a personalised diagnosis or treatment plan.

Original educational diagram for Perimenopause and Menopause
Original educational diagram created for this topic. It explains the care pathway visually and is not a diagnostic image.
Evidence check • 21 July 2026

Menopause care should match symptoms, health risks, and personal priorities

For most people over 45 with typical symptoms, the diagnosis is clinical; a single hormone test rarely explains the whole transition.

  • Systemic menopausal hormone therapy is the most effective treatment for hot flushes and night sweats when benefits outweigh individual risks.
  • If the uterus is present, systemic estrogen usually needs progestogen to protect the endometrium. Low-dose local vaginal estrogen may be considered for isolated vaginal or urinary symptoms.
  • Non-hormonal prescription options and practical measures are available when hormone therapy is unsuitable or not preferred.
  • Any bleeding after 12 months without periods should be assessed rather than assumed to be part of menopause.

What changes

Perimenopause may involve irregular cycles, hot flushes, sleep disturbance, mood changes and vaginal or urinary symptoms.

Assessment

Symptoms and age often guide diagnosis, but testing may be needed when symptoms are atypical, occur early or another condition is possible.

Treatment choices

Options may include lifestyle measures, non-hormonal medicines, vaginal treatments or menopausal hormone therapy after individual benefit-risk assessment.

Deeper clinical context

A personalised menopause consultation

Symptoms and risk profile

Vasomotor, sleep, mood, sexual, urinary and musculoskeletal symptoms are considered alongside cardiovascular, bone, breast and clotting history.

HRT is not one treatment

Choice of oestrogen route, dose and progestogen depends on the uterus, bleeding pattern, migraine, thrombosis risk and preference. Review is essential after starting or changing therapy.

Long-term health

Bone health, physical activity, blood pressure, lipids, smoking and alcohol remain relevant whether or not hormone therapy is used.

When to seek urgent careBleeding after 12 months without a period, very heavy bleeding, chest pain or sudden neurological symptoms requires prompt medical assessment.
Medical note: Individual assessment is essential when symptoms are new, severe, persistent or changing.